论文部分内容阅读
[目的]探讨鼻咽癌调强放疗过程中剂量变化方案及其疗效评价。[方法]对2009年2月～2010年4月入住某院并经过病理诊断证实鼻咽癌患者72例,随机分为A、B、C3个调强剂量组,每组患者24例,各个组别分别采取不同的调强放疗方案。分别在放疗23次结束时、放疗23次结束后3个月、6个月、12个月时对所有患者的口干程度进行跟踪随访和记录。同时在放疗23次结束后12个月对患者的肿瘤消退情况及12月患者生存率进行统计分析。[结果]A组在多数组织器官中的照射剂量高于其余两组,并且对患者腮腺造成的损伤较大。3个组别在疗效方面差异无统计学意义(P﹥0.05)。[结论]A组治疗方案强度过高,需要改进,而B、C两组的治疗方案差别不明显,均适合在鼻咽癌放疗中应用。
[Objective] To investigate the dosage regimen and evaluation of the therapeutic effect of IMRT in nasopharyngeal carcinoma. [Methods] From February 2009 to April 2010 admitted to a hospital and pathologically confirmed 72 cases of nasopharyngeal carcinoma patients were randomly divided into A, B, C3 dose-adjusted dose group, 24 patients in each group, each group Do not take different IMRT programs. Follow-up and recording were performed on the dry mouth of all patients at the end of 23 radiotherapy, 3 months, 6 months and 12 months after the end of 23 radiotherapy. At the same time in the radiotherapy after the end of 23 times 12 months of patients with tumor regression and 12-month survival rate of patients were statistically analyzed. [Results] The radiation dose of group A was higher than that of the other two groups in most tissues and organs, and the damage to the parotid gland was larger. There was no significant difference in efficacy between the three groups (P> 0.05). [Conclusion] The intensity of treatment regimen in group A is too high and needs to be improved. However, there is no obvious difference between groups B and C in the treatment regimens, which are all suitable for radiotherapy of nasopharyngeal carcinoma.