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目的着重于分析甲状腺功能减退性心脏病患者结合小剂量磷酸肌酸钠与甲状腺素治疗的临床效果。方法将我院2014年2月至2016年5月收治的80例甲状腺功能减退性心脏病患者按随机数字法分为实验组和对照组各40例,实验组采用甲状腺素结合小剂量磷酸肌酸钠治疗,对照组单用甲状腺素治疗,比较两组LDH、CK-MB、CK、LVEF、SV、HR等指标。结果两组HR无显著性差异(P>0.05);实验组LDH为(143.6±28.9)U/L,CK-MB为(11.4±5.7)U/L,CK为(114.6±45.7)U/L,LVEF为(53.7±8.2)%,SV为(58.3±6.2)ml,明显优于对照组,差异显著(P<0.05),具有统计学意义。结论甲状腺素结合小剂量磷酸肌酸钠治疗甲状腺功能减退性心脏病,效果确切,临床指标能够显著改善,临床应用价值极高。
The purpose of this study was to analyze the clinical effects of combining low-dose sodium creatine phosphate and thyroxine in patients with hypothyroidism. Methods Eighty patients with hypothyroidism admitted from February 2014 to May 2016 in our hospital were divided into experimental group and control group according to random number method. Forty cases in each group were treated with thyroxine combined with low dose of creatine phosphate Sodium in the control group was treated with thyroxine alone. The indexes of LDH, CK-MB, CK, LVEF, SV and HR were compared between the two groups. Results The LDH of the experimental group was (143.6 ± 28.9) U / L, the CK-MB was (11.4 ± 5.7) U / L and the CK was (114.6 ± 45.7) U / L , LVEF was (53.7 ± 8.2)%, SV was (58.3 ± 6.2) ml, which was significantly better than that of the control group (P <0.05), with statistical significance. Conclusions Thyroxine combined with low dose of sodium creatine phosphate in the treatment of hypothyroidism has definite effect, clinical indexes can be significantly improved, and clinical value is very high.