论文部分内容阅读
作者报道21例HBsAg阳性慢活肝采用免疫抑制(强的松±硫唑嘌呤)疗法治疗前后DNA多聚酶活性。HBsAg滴度和SGOT的变化。每例病人减量治疗6—10周内DNA多聚酶活力下降,8例测不到,并伴HBsAg滴度下降。21例病人中17例HBsAg滴度下降,3例无变化,1例上升。当免疫抑制剂停用时SGOT偶然上升,平均升高2.7倍,但此时常伴DNA多聚酶活力下降。8例DNA多聚酶阴性者最终SGOT下降62%左右,13例DNA多
The authors reported that 21 cases of HBsAg-positive slow-survival liver using immunosuppressive (prednisone azathioprine) therapy before and after treatment of DNA polymerase activity. HBsAg titer and SGOT changes. DNA polymerase activity was reduced in 6-10 weeks for each patient and 8 cases were undetectable, accompanied by a decrease in HBsAg titer. Twenty-one of the 21 patients had a decreased HBsAg titer, 3 had no change, and 1 had an increase. SGOT occasionally increased when immunosuppressants were discontinued, an average increase of 2.7-fold, but this time often accompanied by DNA polymerase activity decreased. DNA polymerase negative in 8 cases eventually SGOT decreased by about 62%, 13 cases of DNA more