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我院内科血液病研究室于1978年观察了新药1,2:5,6二去水卫矛醇(以下简称二去水卫矛醇)对慢性粒细胞白血病(简称慢粒)的疗效。现将这些病例的治疗情况初步小结报道如下。资料和方法慢粒5例中,男性3例,女性2例,年龄20～47岁,经血象和骨髓象检查确诊,其中仅1例以往曾用马利兰治疗,因病情有反复故换用二去水卫矛醇治疗。 5例患者均诉述有疲乏、乏力及盗汗等。脾肿大的程度自肋下1.5公分至深入骨盆,肝和淋巴结肿大的程度自可及至轻度肿大。血象和骨髓象如后(血红蛋白为6～11克％,白细胞计数为3.9～30.5万/立方毫米,原粒+早幼粒之和为3～9％,中幼粒+晚幼粒之和为15～35％,血小板计数为12～37万/立方毫米,髓象增生程度为明显活跃至极度活跃,粒红之比
Laboratory of Internal Medicine Hematology Laboratory in 1978 observed the new drug 1,2: 5,6 dianhydrogalactitol (hereinafter referred to as two water dulcitol) on chronic myelogenous leukemia (CML) effect. The treatment of these cases are now preliminary summary report as follows. Materials and Methods CML in 5 cases, 3 males and 2 females, aged 20 to 47 years old, diagnosed by blood and bone marrow examination, of which only 1 case had been treated with Maryland, because the disease is repeatedly used instead Hydrogalanate treatment. All 5 patients complained of fatigue, fatigue and night sweats. The degree of splenomegaly from the rib 1.5 cm deep into the pelvis, liver and lymphadenopathy to a mild degree of swollen. Blood and bone marrow like after (hemoglobin is 6 to 11 grams%, white blood cell count of 3.9 to 305,000 / cubic millimeter, the sum of protoplasm + promyelocytic granules is 3 ~ 9%, the sum of juvenile + late promyelocytic 15 ~ 35%, platelet count 12 ~ 370,000 / cubic mm, medullary hyperplasia was significantly active to extremely active, the ratio of grainy