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目的:观察补阳还五汤加阿托伐他汀治疗糖尿病周围神经病变(DPN)的临床疗效。方法:将60例DPN患者随机分为两组,对照组30例单用阿托伐他汀治疗,治疗组30例在对照组治疗基础上加补阳还五汤治疗。两组均治疗3个月后比较两组临床疗效、血脂及神经传导速度。结果:总有效率治疗组为90.0%,对照组为63.3%,组间比较,差异有统计学意义(P<0.01);两组周围神经传导速度比较,差异有统计学意义(P<0.01);两组血脂各项指标治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05)。结论:补阳还五汤联合阿托伐他汀治疗糖尿病周围神经病变可显著改善患者临床症状,提高神经传导速度,疗效确切。
Objective: To observe the clinical efficacy of Buyang Huanwu Decoction plus atorvastatin in the treatment of diabetic peripheral neuropathy (DPN). Methods: Sixty patients with DPN were randomly divided into two groups. 30 patients in the control group were treated with atorvastatin alone and 30 patients in the control group were treated with BYHWD on the basis of the control group. After three months of treatment, the clinical efficacy, blood lipid and nerve conduction velocity were compared between the two groups. Results: The total effective rate was 90.0% in the treatment group and 63.3% in the control group. There was significant difference between the two groups (P <0.01). There was a significant difference in the peripheral nerve conduction velocity between the two groups (P <0.01) ; The two groups of blood lipid indicators before and after treatment in the group comparison and after treatment comparison, the difference was statistically significant (P <0.05). Conclusion: Buyang Huanwu Decoction combined with atorvastatin in diabetic peripheral neuropathy can significantly improve the clinical symptoms of patients and improve the nerve conduction velocity, the exact effect.