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目的:观察中枢神经系统肠源性囊肿的组织形态及免疫组织化学特征。方法:使用病理组织学及免疫组织化学方法对31例中枢神经系统不同部位的肠源性囊肿进行研究。结果:囊肿壁上皮可为单层或复层扁平、立方、柱状上皮;一些病例可见两种以上上皮组织成分,并相互移行;某些病例,在囊肿壁内可含有黑色素、软骨、平滑肌、粘液腺等多种组织成分。免疫组织化学染色EMA均呈阳性;CEA染色仅一例阴性,而此例NSE阳性,故应诊断为神经上皮性囊肿;S-100和CK染色结果不固定;Vi-mentin和GFAP均呈阴性。结论:肠源性囊肿的组织形态和免疫组织化学特点可作为鉴别其他类型囊肿的依据。
Objective: To observe the histomorphological and immunohistochemical features of intestinal cysts in the central nervous system. Methods: 31 cases of intestinal cysts in different parts of the central nervous system were studied using histopathology and immunohistochemistry. RESULTS: The cyst wall epithelium may be monolayer or multilamellar, flat, cubic, and columnar epithelium; in some cases, two or more epithelial components may be seen and migrated to each other; in some cases, melanin, cartilage, smooth muscle, mucus may be contained in the wall of the cyst. Gland and other tissue components. Immunohistochemical staining for EMA was positive; CEA staining was only negative in one case, but this case was positive for NSE, so it should be diagnosed as a neuroepithelial cyst; S-100 and CK staining results were not fixed; Vi-mentin and GFAP were negative. Conclusion: The histomorphological and immunohistochemical features of intestinal cysts can be used as the basis for identifying other types of cysts.