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动物实验发现,免疫调节剂来氟米特(leflunomide)可有效抑制关节炎的病情进展。为进一步评价该药对急性类风湿性关节炎(RA)病人的疗效和安全性并与已知有效药物柳氮磺吡啶(sulfasalazine,SASP)对比,作者进行了随机、双盲、安慰剂对照、?
Animal experiments found that the immunomodulator leflunomide (leflunomide) can effectively inhibit the progression of the disease. To further evaluate the efficacy and safety of this drug in patients with acute rheumatoid arthritis (RA) and compare it to the known active drug sulfasalazine (SASP), the authors randomized, double-blind, placebo- ?