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目的:评价全程硬膜外镇痛术对新生儿安全性的影响。方法:收集本院随机分配40例无产科及硬膜外阻滞禁忌证的单胎初产妇,随机分为2组,每组20例。Ⅰ组为常规分娩镇痛组,Ⅱ组为全程分娩镇痛组。对两组产妇行硬膜外阻滞,分别观察子宫收缩情况,总产程,分娩方式,新生儿血气分析,体重及新生儿阿氏评分。结果:Ⅱ组在实施镇痛后30 min时子宫收缩力抑制最明显(P<0.05),但过后可逐渐恢复至正常水平。共5例需行剖宫产,剖宫产产妇的宫缩加强情况与两组中阴道分娩产妇宫缩加强差异无统计学意义(P<0.05),两组的第二、三产程、分娩方式、新生儿阿氏评分、体重、脐静脉血气分析及新生儿转归等比较差异无统计学意义(P>0.05)。结论:分娩全程硬膜外镇痛无延长第二、三产程时间,对新生儿无影响。
PURPOSE: To evaluate the effect of total epidural analgesia on neonatal safety. Methods: A total of 40 singleton primiparous women randomly assigned 40 obstetric and epidural contraindications were randomly divided into 2 groups (20 in each group). Group Ⅰ was routine labor analgesia group, Group Ⅱ was full labor analgesia group. The two groups of maternal epidural block were observed uterine contraction, total labor, mode of delivery, neonatal blood gas analysis, body weight and neonatal Ah’s score. Results: In the group Ⅱ, the contractility of the uterus was most obvious at 30 min after the analgesia (P <0.05), but gradually recovered to the normal level afterwards. A total of 5 cases required cesarean, cesarean maternal contractions and vaginal delivery maternal contractions between the two groups no significant difference (P <0.05), the two groups of the second and third labor, mode of delivery Newborns, Asahi score, body weight, umbilical vein blood gas analysis and neonatal outcomes were no significant difference (P> 0.05). Conclusion: The whole delivery of epidural analgesia without prolonging the second and third labor time, no effect on the newborn.