论文部分内容阅读
目的:观察奥美拉唑、左氧氟沙星、阿莫西林三联疗法治疗消化性溃疡,根除幽门螺杆菌(Hp)的疗效。方法:选择90例Hp阳性消化性溃疡患者,随即分为观察组与对照组。观察组采用奥美拉唑、左氧氟沙星、阿莫西林三联疗法,治疗1周后继续服用奥美拉唑20 mg 3周。对照组采用奥美拉唑、甲硝唑、阿莫西林三联疗法,治疗1周后,继续服用奥美拉唑3周。治疗4周后比较两组溃疡愈合情况和Hp根除情况。结果:观察组和对照组溃疡愈合情况无统计学差异(P>0.05);Hp根除率,观察组和对照组分别是91.3%、54.5%,差异有统计学意义(P<0.05)。结论:奥美拉唑、左氧氟沙星、阿莫西林三联疗法是根除幽门螺杆菌(Hp),治疗消化性溃疡的理想方案。
Objective: To observe the curative effect of omeprazole, levofloxacin and amoxicillin triple therapy on peptic ulcer and eradication of Helicobacter pylori (Hp). Methods: 90 cases of Hp positive peptic ulcer patients were randomly divided into observation group and control group. The observation group was treated with omeprazole, levofloxacin and amoxicillin triple therapy. After 1 week of treatment, omeprazole 20 mg was given for 3 weeks. Control group with omeprazole, metronidazole, amoxicillin triple therapy, after 1 week of treatment, continue taking omeprazole for 3 weeks. Four weeks after treatment, ulcer healing and Hp eradication were compared between the two groups. Results: There was no significant difference in ulcer healing between observation group and control group (P> 0.05). The eradication rate of Hp in observation group and control group was 91.3% and 54.5% respectively, with statistical significance (P <0.05). Conclusion: Omeprazole, levofloxacin, amoxicillin triple therapy is the ideal solution to the eradication of Helicobacter pylori (Hp) in the treatment of peptic ulcer.