随着工业和交通运输业的发展,环境铅污染问题日益突出,评价人群环境铅暴露水平,早期发现铅污染对人群健康的影响是预防环境铅污染危害的重要课题。 由于侵入人体的铅对δ-氨基乙酰丙酸脱水酶的抑制,阻断了δ-氨基乙酰丙酸合成卟胆原,使δ-ALA在血液中的浓度升高,并随尿排出,所以可通过检查人尿中δ-ALA的含量来评价人体内铅负荷情况。监测尿δ-ALA有方法简便、易于掌握、样品采集容易、易于接受、适于进行大规模的调查等 With the development of industry and transportation industry, the problem of environmental lead pollution has become increasingly prominent. To assess the environmental lead exposure of the population, early detection of the impact of lead pollution on human health is an important issue in preventing environmental lead pollution. As the lead invaded the body of δ-aminolevulinic acid dehydratase inhibition, blocking the synthesis of δ-aminolevulinic acid porphyrin, so that the concentration of δ-ALA in the blood, and with the urine, so the By examining the content of δ-ALA in human urine to assess the body’s lead load. Urinary δ-ALA monitoring method is simple, easy to grasp, sample collection is easy, easy to accept, suitable for large-scale investigations