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目的探讨蒙古族人群高血压患者血浆肾素活性(PRA)和血管紧张素Ⅱ(AngⅡ)与缺血性心电图的关系。方法在蒙古族人群高血压现况调查的基础上,对468例高血压患者进行心电图检查、PRA和AngⅡ的检测;采用SPSS 13.0软件进行统计分析。结果缺血性心电图表现组的PRA 1.37 ng/(mL.h)低于非缺血性心电图表现组1.38 ng/(mL.h),但差异无统计学意义(均P>0.05)。缺血性心电图表现组的Ang Ⅱ(51.3 pg/mL)低于非缺血性心电图表现组(53.0 pg/mL),但差异无统计学意义(均P>0.05)。经多因素Logistic回归分析,各PRA和AngⅡ水平对缺血性心电图表现的OR值差异均无统计学意义(均P>0.05)。结论在高血压患者中,PRA和AngⅡ水平与缺血性心电图表现均无关联。
Objective To investigate the relationship between plasma renin activity (PRA) and angiotensin Ⅱ (Ang Ⅱ) and ischemic electrocardiogram in Mongolian patients with hypertension. Methods Based on the survey of hypertension in Mongolian population, 468 hypertensive patients were examined by electrocardiogram, PRA and AngⅡ, and SPSS 13.0 software was used for statistical analysis. Results The PRA 1.37 ng / (mL.h) in ischemic electrocardiogram group was lower than that in nonischemic electrocardiogram group (1.38 ng / (mL.h)), but the difference was not statistically significant (all P> 0.05). Ang Ⅱ (51.3 pg / mL) was lower in ischemic ECG group than in non-ischemic ECG group (53.0 pg / mL), but the difference was not statistically significant (all P> 0.05). After multivariate Logistic regression analysis, there was no significant difference in the OR of ischemic electrocardiogram between PRA and AngⅡ (all P> 0.05). Conclusion There is no correlation between PRA and angiotensin Ⅱ (Ang Ⅱ) levels and ischemic ECG in hypertensive patients.