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目的了解北京市海淀区高校在职教职工胃食管反流病(GERD)的患病状况,探讨GERD发生的危险因素。方法 2008年10~12月,采用方便抽样方法 ,使用“中国胃食管反流病协作组”推荐的反流性疾病问卷(reflux diagnostic questionnaire,RDQ)对海淀区三所高校在职教职工进行GERD抽样调查,并对调查结果统计分析。采用SPSS 13.0软件对危险因素进行χ2检验,多因素logistic回归分析,P<0.05为差异有统计学意义。结果海淀区三所高校在职教职工GERD的患病率为0.69%,典型症状发生率为9.57%,单纯症状者占8.88%。运用χ2检验、多因素logistic统计方法 ,被调查人群的健康状态、生活压力、胃肠道疾病和胃肠肿瘤家族史对GERD患病率影响具有统计学意义。结论与普通人群相比,海淀区高校在职教职工人群GERD患病率相对较低,典型症状发生率相差不大,但单纯症状的发生率较高。健康状态、生活压力以及胃肠道疾病和胃肠肿瘤家族史为GERD的危险因素。
Objective To investigate the prevalence of gastroesophageal reflux disease (GERD) among serving staff in institutions of higher learning in Haidian District, Beijing and explore the risk factors of GERD. Methods From October to December of 2008, three sampling methods were used to investigate the effect of reflux diagnostic questionnaire (RDQ) on the three teaching staffs in Haidian District, using the “China Gastroesophageal Reflux Disease Cooperative Group” GERD sampling survey, and statistical analysis of the survey results. SPSS 13.0 software was used to test the risk factors byχ2 test, multivariate logistic regression analysis, P <0.05 was considered statistically significant. Results The prevalence of GERD among serving staff in three colleges and universities in Haidian District was 0.69%. The incidence of typical symptoms was 9.57% and that of simple symptoms was 8.88%. The use of χ2 test, multivariate logistic statistical methods, the health status of the surveyed population, life stress, gastrointestinal diseases and family history of gastrointestinal cancer have a statistically significant effect on the prevalence of GERD. Conclusions Compared with the general population, the prevalence of GERD among serving staff in institutions of higher learning in Haidian is relatively low, and the incidence of typical symptoms is similar but the incidence of simple symptoms is higher. Health status, life stress and family history of gastrointestinal disease and gastrointestinal cancer are risk factors for GERD.