论文部分内容阅读
在极其严格和标准的条件下,比较研究了环丙沙星(ciprofloxacin)、培氟沙星(pefloxacin)和丁胺卡那霉素(amikacin)对体重19.5～20.0g的健康纯种成鼠肠道菌丛的影响及合并幽门螺旋菌病的十二指肠溃疡病患者的治疗作用。发现三种抗菌药物中,环丙沙星疗效最佳,维持时间最长;而且,不同剂量的环丙沙星均能充分杀灭动物肠道的杆菌属和葡萄球菌,明显减少肠球菌,但对有益于机体的乳酸杆菌影响很小。小鼠肠道菌丛的恢复与环丙沙星的剂量有密切关系:每公斤体重接受10mg的小鼠,肠杆菌属、葡萄球菌和肠球菌只需在停药后的第25天即完全恢复;而每公
Under extremely stringent and standard conditions, the effects of ciprofloxacin, pefloxacin, and amikacin on healthy purebred rats weighing 19.5-20.0 g Road flora and the impact of combined treatment of Helicobacter pylori in patients with duodenal ulcer disease treatment. It was found that ciprofloxacin had the best curative effect and the longest maintenance time among the three antibacterials. Moreover, ciprofloxacin at different dosages could all kill Bacillus and staphylococci in the intestine of animals and significantly reduce enterococci, Lactobacillus beneficial to the body has little effect. The recovery of mouse intestinal flora is closely related to the dose of ciprofloxacin: mice receiving 10 mg / kg of body weight, Enterobacter, Staphylococcus and Enterococci need only be recovered completely on the 25th day after withdrawal ; And each person