急性肾缺血通常被认为是缺血急性肾衰(IARF)发病的始动因素或重要因素。临床上许多缺血性疾病如大失血、休克、严重创伤、挤压综合征、大手术后、败血症以及产科意外等常常因急性肾缺血而诱发IARF,其中败血性休克,产后出血以及主动脉或胆管手术尤为突出。该损伤一般是指缺血缺氧期(或低氧期)的损伤;缺血后血液再灌流时,也可引起组织损伤,称为缺血过程中的再灌流损伤。广义的缺血性损伤包 Acute renal ischemia is usually considered as a primary factor or an important factor in the pathogenesis of IARF. Clinically, many ischemic diseases such as severe blood loss, shock, severe trauma, crush syndrome, major surgery, sepsis and obstetric accidents are often caused by acute renal ischemia and IARF, including septic shock, postpartum hemorrhage and the aorta Or biliary surgery is particularly prominent. The injury is generally refers to the injury during ischemia and hypoxia (or hypoxia); ischemic postreperfusion can also cause tissue damage, called reperfusion injury during ischemia. Generalized ischemic injury package