论文部分内容阅读
急性腹泻是发展中国家乳幼儿死亡的主要病因之一.其病因有感染性及非感染性二类.前者由细菌、病毒、霉菌或寄生虫引起,后者包括过敏性腹泻及吸收不良性腹泻等.病原体:以埃希氏大肠杆菌、空肠弯曲菌、输状病毒及沙门氏菌为最常见.埃希氏大肠杆菌肠炎:引起腹泻的埃希氏大肠杆菌有三种类型:致病性大肠杆菌(EPEC),产肠毒素大肠杆菌(ETEC)和侵袭性大肠杆菌(EIEC).EPEC 附着于肠表面,破坏肠微绒毛,在小肠上皮细胞繁殖,引起局部炎症及腹泻.ETEC 不侵入肠壁粘膜上皮细胞,在小肠腔内繁殖,产生耐热毒素(ST)与不耐热毒素(LT).
Acute diarrhea is one of the leading causes of death in young and middle-aged children in developing countries, and its causes are infectious and non-infectious, the former being caused by bacteria, viruses, molds or parasites, the latter including allergic diarrhea and malabsorptive diarrhea Etc. Pathogens: Escherichia coli, Campylobacter jejuni, Vibrio parahaemolyticus and Salmonella are most common Escherichia coli enteritis: There are three types of Escherichia coli causing diarrhea: pathogenic Escherichia coli (EPEC ), Enterotoxigenic Escherichia coli (ETEC), and invasive Escherichia coli (EIEC) .EPEC attaches to the intestinal surface, destroying intestinal microvilli and multiply in the small intestine epithelial cells, causing local inflammation and diarrhea. ETEC does not invade intestinal mucosal epithelial cells , Multiply in the small intestine cavity producing heat toxin (ST) and heat labile toxin (LT).