配制大输液时,一般只对成品作热原试验。对灌装前的大输液中间体,历来均不作热原试验。实际工作中,我们体会到在灌装前检测大输液中间体的热原,有时具有重大意义。因为如果在此中间体中测得含有热原时,为了避免造成该批输液的经济损失,可以采取一些补救措施。即使无法挽救时,也可以省去灌装、封口、消毒、检查、包装等工序。 Preparation of large infusion, the general only for the finished pyrogen test. Infusion of large infusion of intermediates, has never been pyrogen test. In actual work, we realize that it is sometimes of great significance to detect the pyrogen of large infusion intermediates before filling. Because, if pyrenes were detected in this intermediate, some remedial action could be taken to avoid the economic loss of the infusion. Even if you can not save, you can save filling, sealing, disinfection, inspection, packaging and other processes.