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目的探讨心肌肌钙蛋白 I(cTnI)在急性一氧化碳中毒(ACOP)患者心肌损伤早期诊断中的意义及其对心脏事件发生率的检测作用、方法将48例本院 ACOP 患者分 A 组(轻度)、B 组(中度)、C 组(重度)三组,于接诊后3h 内检测 cTnI、心肌酶学、心电图(ECG),比较 cTnI 和其他单项指标或综合指标对三组 ACOP 患者心肌损伤早期检出率的差异性。结果 C 组 cTnI 明显高于 A 组、B 组,差异有显著性(P<0.01),B 组亦高于 A 组,差异性有显著性(P<0.05),心肌酶学及 ECG 于各组问无差异性(P>0.05)。cTnI 升高的例数显著高于单一或综合指标异常例数(P<0.05)。结论应用血清 cTnI 检测方法能提高 ACOP 患者心肌损伤的早期检出率,其灵敏度高于心肌酶学和心电图检查。
Objective To investigate the significance of cardiac troponin I (cTnI) in the early diagnosis of myocardial injury in patients with acute carbon monoxide poisoning (ACOP) and its effect on the incidence of cardiac events. Methods 48 cases of ACOP in our hospital were divided into group A ), Group B (moderate) and group C (severe). The levels of cTnI, myocardial enzymes, electrocardiogram (ECG), cTnI and other single or combined indexes were measured within 3h after admission. Differences in early detection rate of injury. Results The cTnI in group C was significantly higher than that in group A and group B (P <0.01), and also higher in group B than in group A (P <0.05). The levels of myocardial enzymes and ECG in each group Ask no difference (P> 0.05). The number of patients with elevated cTnI was significantly higher than those with single or composite abnormalities (P <0.05). Conclusion The application of serum cTnI detection method can improve the early detection rate of myocardial injury in ACOP patients, and its sensitivity is higher than that of myocardial enzymology and electrocardiogram.