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槟榔花口服液急性毒性实验，４、鼠灌胃给药的ＬＤ＿（５０）为（１８．８７±４．３）ｇ／ｋｇ体重，皮下给药的ＬＤ＿（５０）为（９．７６±１．７）ｇ／ｋｇ体重，大鼠长期毒性实验分别灌胃给药２．６６ｇ／ｋｇ，５．３３ｇ／ｋｇ和１０．６５ｇ／ｋｇ体重，对照组给予等容积的蒸馏水，连续２周，各组无动物死亡，各项血指标检查正常。病理报告高剂量组有３只动物少量肝细胞可见脂肪空泡，１只大鼠肺脏轻度灶性肺炎，中低剂量组无明显改变。高剂量组存活动物于停药７天后，病理检查均正常。
The acute toxicity test of the betel nut oral liquid, 4, the LD 50 of intragastric administration was (18.87 ± 4.3) g / kg body weight and the subcutaneous LD 50 was 9.76 ± 1 .7) g / kg body weight, rats long-term toxicity were intragastrically administered 2.66g / kg, 5.33g / kg and 10.65g / kg body weight, the control group was given an equal volume of distilled water for two weeks, each No animals died, all blood tests were normal. Pathological reports of high-dose group of three animals showed a small number of hepatocytes fat vacuoles, a lung of mild focal pneumonia in rats, medium and low dose group no significant change. High-dose group of surviving animals in the withdrawal of 7 days after the pathological examination were normal.