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采用施他宁２５０μｇ静脉推注，再以２５０μｇ／ｈ连续静脉滴注，维持治疗门脉高压食管静脉曲张破裂大出血者１９例。结果：１２小时内出血停止者１６例，止血率８４．２％（１６／１９），３例仅有少量渗血。待出血基本控制后再注射硬化剂，胃及食管内潴留液很少，视野清晰，１９例全部完成硬化疗法。应用施他宁后食管静脉及门静脉宽度分别缩小３８．３％及３４．４％，均有显著差异（Ｐ＜０．０１）。施他宁显著地减少胃液分泌和升高胃液ｐＨ（Ｐ＜０．０１）。提示，施他宁的止血作用除与减少内脏血流量、降低门静脉压力有关外，与减少胃液分泌和降低胃酸也有关。
Twenty patients were treated with intravenous injection of 250mg / h of Sitafryin, and 19 patients were treated with intravenous infusion of 250μg / h esophageal variceal bleeding. Results: 16 cases stopped bleeding within 12 hours, bleeding rate was 84.2% (16/19), 3 cases only a small amount of bleeding. To be basic control of bleeding after injection of sclerotherapy, stomach and esophageal retention fluid rarely, clear vision, 19 cases of complete sclerotherapy. The esophageal and portal vein width decreased 38.3% and 34.4% respectively after application of shitutin (P <0.01). Shitainin significantly reduced gastric secretion and increased gastric pH (P <0.01). Tip, Shi Taining hemostatic effect in addition to reducing visceral blood flow, reduce portal pressure related to reducing gastric juice secretion and reduce gastric acid also.