论文部分内容阅读
目的:通过高效液相色谱比较自制与不同产地六神曲的指纹图谱,得出其指纹图谱相似度及共有峰个数。方法:通过对自制与不同产地六神曲粉末甲醇超声提取部位进行高效液相指纹图谱分析,以自制六神曲为参照图谱,采用中药指纹图谱相似度评价系统做相似度评价。结果:得出各个产地指纹图谱的相似度值为0.689(安徽)、0.574(湖北)、0.347(江苏)、0.579(上海)、0.456(北京)、0.501(河南)、0.684(吉林)、0.568(山西)、0.135(辽宁)、0.609(四川)、0.191(浙江)以及4共有峰。结论:不同产地的六神曲质量不一,指纹图谱的方法可以为其质量标准提供科学依据。
OBJECTIVE: To compare the fingerprints of Liushen Qu in homemade and different habitats by high performance liquid chromatography (HPLC), and to get the similarity of fingerprint and the number of common peaks. Methods: The HPLC-MS fingerprint of Liushen Qu powder powder from homemade and different producing areas was analyzed by high performance liquid chromatography (HPLC), and the self-made Liushen Qu was taken as the reference map. The similarity evaluation was conducted by using the Chinese medicine fingerprint similarity evaluation system. Results: The similarity of fingerprints of each origin was 0.689 (Anhui), 0.574 (Hubei), 0.347 (Jiangsu), 0.579 (Shanghai), 0.456 (Beijing), 0.501 (Henan), 0.684 (Jilin) Shanxi), 0.135 (Liaoning), 0.609 (Sichuan), 0.191 (Zhejiang) and 4 common peaks. Conclusion: The quality of Liushen in different areas is different, and the method of fingerprinting can provide a scientific basis for its quality standard.