约在半个世纪前已有作者提出慢性鼻阻塞可使血氧饱和受到不利影响,用口呼吸可使肺换气量减低,导致血中碱储备下降,扰乱血液的酸碱平衡。临床和实验研究证明鼻腔对同侧胸廓及支气管肌具有反射性影响,Noonan 等1965年讨论了儿童期继发于上呼吸道阻塞的心肺改变和换气不足综合征。也有作者们报告摘除肥大的增殖体和扁桃体改善上呼吸道阻塞情况之后,可以使动脉血氧和二氧化碳张力得到改善或恢复正常。Cassisi 等报告鼻衄患者填塞鼻腔后动脉血氧分压(PO_2)明显降低,其他一些作者也观察到前后鼻孔填塞的鼻衄患者、手术后鼻腔填塞及健康 About half a century ago, some authors suggested that chronic nasal obstruction can adversely affect oxygen saturation. Breathing through the mouth can reduce the amount of lung ventilation, leading to the decline of alkaline reserve in the blood and disrupt the acid-base balance of the blood. Clinical and experimental studies have shown that the nasal cavity has a reflective effect on the ipsilateral thoracic and bronchial muscles. Noonan et al. 1965 discussed cardiopulmonary changes and hypopnea syndrome secondary to upper airway obstruction in childhood. There are also reports that hypertrophy of proliferative bodies and amygdala improves upper airway obstruction after the authors have reported that arterial oxygen and carbon dioxide tension can be improved or returned to normal. Cassisi et al reported that epistaxis was significantly reduced in patients with epistaxis after filling the nasal cavity. Other authors also observed epistaxis in patients with nasal congestion before and after nasal packing, nasal packing and health after surgery