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目的：观察谷胱甘肽对肝癌栓塞化学疗法（化疗）后的护肝效果。方法：对超液化碘油抗癌药混悬剂栓塞化疗后的原发性肝癌１００例，随机分为对照组与谷胱甘肽组，每组各５０例。对照组用肝用复合氨基酸注射液２５０ｍＬ，葡醛内脂０．４ｇ，门冬氨酸钾镁１５ｍＬ，均静脉滴注（静滴），ｑｄ为基础治疗。谷胱甘肽组在对照组基础治疗上加用谷胱甘肽１．２ｇ，静滴，ｑｄ，疗程均为１０～１４ｄ。结果：３ｗｋ后提示，对照组ＡＬＴ，ＡＳＴ，ｒ＿ＧＴ均明显上升（Ｐ＜０．０１），治疗组上升不明显（Ｐ＞０．０５）；对照组ＡＬＢ明显下降（Ｐ＜０．０５），治疗组有上升但无统计学意义。组间比较上述改变差别亦有非常显著意义（Ｐ＜０．０１）。结论：谷胱甘肽对肝癌栓塞化疗后的病人具有明显护肝作用。
Objective: To observe the effect of glutathione on liver protection after chemotherapy (chemotherapy) of liver cancer embolization. Methods: One hundred cases of primary liver cancer after embolization chemotherapy with lipiodol anti-cancer drug suspension were randomly divided into control group and glutathione group, 50 cases in each group. In the control group, 250 mg of compound amino acid injection for liver, 0.4 g of glucuronide and 15 mg of magnesium aspartate were intravenously infused (intravenously), and qd was used as a basis for treatment. In the glutathione group, glutathione was added to the basic treatment of the control group by 1.2 g, intravenous infusion, qd, and the course of treatment was 10 to 14 days. Results: After 3 weeks, the levels of ALT, AST, and r_GT in the control group increased significantly (P<0.01), but there was no significant increase in the treatment group (P>0.05). The ALB in the control group decreased significantly (P<0.05). The treatment group increased but was not statistically significant. The differences between the groups were also significantly different (P<0.01). Conclusion: Glutathione has significant hepatoprotective effect on patients with hepatocellular carcinoma after embolization chemotherapy.