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目的:为了验证微量营养素饮料能够提供给儿童日常所需的铁和锌的假设。研究设计:对40名6-9岁儿童进行了研究(利马,秘鲁)。4周内,受试儿童每天饮用含有多种微量营养素的饮料。之后连续2 d,受试儿童饮用稳定同位素标记的饮料并接受一次静脉锌注射,其中一部分儿童加餐一次。用质谱测量法评估铁和锌的生物利用度。结果:额外加餐的儿童,其铁的吸收率明显低于没有吃饭的儿童(9.8%±6.7% vs 11.6%±6.9%, P=0.04),但锌的吸收率的差异则不显著(24.5%±10.7% vs 22.8%±7.6%,P=0.2)。另外,每天给予儿童的微量营养素饮料能够基本满足其所需的铁和锌的量。结论:每天提供多营养素的饮料能够基本满足年幼儿童对矿物质的需求。食物对铁的吸收有一些抑制作用,但对锌则没有;因此,即使在吃饭的情况下,饮用这些饮料是有益的。
Purpose: To validate the hypothesis that micronutrient beverages provide iron and zinc that children routinely need. Study Design: Forty children aged 6-9 years were studied (Lima, Peru). Within 4 weeks, children under test drank a wide range of micronutrients. After 2 consecutive days, children under test drank stable isotope labeled beverages and received a single intravenous injection of zinc, some of which were given once. Bioavailability of iron and zinc was assessed by mass spectrometry. RESULTS: Children who dined extra meal had significantly lower rates of iron absorption than those who did not eat (9.8% ± 6.7% vs 11.6% ± 6.9%, P = 0.04), but the difference in zinc absorption was insignificant (24.5 % ± 10.7% vs 22.8% ± 7.6%, P = 0.2). In addition, micronutrient beverages given daily to children substantially meet the amount of iron and zinc they require. CONCLUSIONS: Daily multi-nutrient beverages meet the basic mineral needs of young children. Food has some inhibitory effect on the absorption of iron, but not on zinc; therefore, it is beneficial to drink these beverages, even when eating.