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Desmoid-type fibromatoses are clonal fibroblasticproliferations that arise in deep soft tissues and arecharacterized by infiltrative growth and a tendencytoward local recurrence.The molecular genetic studiesshow that there are chromosomal abnormalities relatingto the pathogenesis of this lesion,such as trisomy 8.~1However,there are different results concerning this typeof abnormality.Fluorescence in situ hybridization(FISH)is a sensitive and reproducible technique that combinesmolecular cytogenetics with morphologic informationand brings them together in a single frame forevaluation.~2 To explore the controversy of the aneuploidabnormality of chromosome 8,we collected specimens ofdesmoid-type fibromatosis to determine whether the
Desmoid-type fibromatoses are clonal fibroblastic proteins are and characteristic characterized by infiltrative growth and a tendency to act as local recurrence. different results concerning this type of abnormality. Fluorescence in situ hybridization (FISH) is a sensitive and reproducible technique that combines molecular cytogenetics with morphologic information and brings them together in a single frame forevaluation. ~ 2 To explore the controversy of the aneuploidabnormality of chromosome 8, we collected specimens ofdesmoid-type fibromatosis to determine whether the