细胞内多数的大分子都缺乏特异的形态学特征与组织化学反应,但多数细胞大分子都具有抗原性,可以利用它们与各自抗体结合的特异性来进行鉴别和定位。从理论上说,现代电子显微镜的分辨本领完全可以看到与抗原结合后的抗体。但使用常规的超薄切片技术,这样的分子集团并不比周围其它大分子的电子密度更高一些。所以为了达到辨别的目的,必须对抗体进行标记。标记抗体技术与各种电镜 Most macromolecules in cells lack specific morphological features and histochemical reactions, but most cell macromolecules are antigenic and can be identified and localized by the specificity of their binding to their respective antibodies. In theory, the resolution of modern electron microscopy can fully see the antibodies that bind to antigens. However, using conventional ultrathin sectioning technology, such molecular groups do not have higher electron density than other macromolecules around them. Therefore, in order to achieve the purpose of identification, antibodies must be labeled. Labeled antibody technology with various electron microscopes