Virchow-Robin间隙是伴随小动脉和更细小的动脉穿行于脑表面的含有脑脊液的蛛网膜下腔的内陷。在儿童期,已于粘多糖病病儿的脑白质内见有扩大的Virchow-Robin间隙,在其内有泡沫细胞使其扩张,但这个发现的临床意义以前未做过研究。作者对连续12个月内接受头颅MRI检查的1250例儿童进行研究,以确定大脑凸面的白质内是否存在扩大的Virchow-Robin间隙及其发生率、部位和临床意义。 The Virchow-Robin gap is a subsidence of cerebrospinal fluid-containing subarachnoid space that traverses the brain surface along with arterioles and finer arteries. In childhood, there have been enlarged Virchow-Robin interstitials within the white matter of mucopolysaccharidoses in which foam cells expand, but the clinical significance of this finding has not been previously studied. The authors studied 1250 children who underwent cranial MRI in a continuous 12-month period to determine whether there was an enlarged virchow-Robin gap in the convex white matter and its incidence, location, and clinical significance.