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目的:评估重症监护病房(ICU)患者红细胞(RBC)输注指征,观察输注后效果及不同输血量与转归之间的联系。方法:回顾性分析2007年我院122例接受RBC输注的ICU患者临床资料,分析每次输血的指征,输注后疗效及影响因素。按RBC输注量多少分为3组(输血量<10U为少量输血组,10～20U为中量输血组,>20U为大量输血组),分别比较各组年龄、平均住院日及转归。结果:约一半输血无明显适应症,不同输血量的患者,转归的差异有统计学意义,1/3患者输血量过多,血红蛋白提升过高。结论:ICU患者接受了大量RBC输注,一半输血无明显适应症,严格执行输血指南和加强临床医师教育培训可有效节约血液。
OBJECTIVE: To assess the indications of red blood cell (RBC) transfusion in intensive care unit (ICU) patients and observe the effect of transfusion and the relationship between different transfusion volumes and outcomes. Methods: The clinical data of 122 ICU patients receiving RBC infusion in our hospital from 2007 to 2007 were retrospectively analyzed. The indication of each transfusion and the therapeutic effect and the influencing factors after transfusion were analyzed. According to the number of RBC infusion divided into 3 groups (blood transfusion <10U for a small amount of blood transfusion group, 10 ~ 20U for the amount of blood transfusion group,> 20U for a large number of blood transfusion group) were compared each group age, average length of stay and outcome. Results: About half of transfusions had no obvious indications. The patients with different transfusion volumes had statistically significant differences in outcome. One third of patients had excessive transfusion and excessively elevated hemoglobin. CONCLUSIONS: ICU patients received a large number of RBC transfusions and no obvious indications for half of the transfusions. Strict guidelines for blood transfusion and clinicians’ education and training can effectively save blood.