A series of Zr63.5-xTixAl9Fe4.5Cu23(x = 0,1.5,3.0,4.5,6.0;at％)bulk metallic glasses(BMGs)were designed and produced by means of copper mold suction casting.The effect of Ti addition on the glass-forming ability(GFA)and mechanical properties of Zr63.5-xTix-Al9Fe4.5Cu23 alloys was first investigated.The glass-forming ability and room-temperature plasticity of BMGs increase first and then reduced with Ti content increasing.At x = 3.0,the Zr60.5Ti3Al9Fe4.5Cu23 BMG showed a critical glass formation diameter of 10 mm and excellent room-temperature compressive plasticity(εP = 4.7％)by using the samples with dimensions of Φ3 mm×6 mm.Meanwhile,the BMG also showed better biocompatibility and biocorrosion resistance compared with Ti6A14V alloy.Under the imitated human body condition,the corrosion current density(Icorr)of BMG was 6.61×10-10 A·cm-2,which is two orders of magnitude lower than that of con-ventional Ti6A14V alloy.Moreover,the CCD-986sk cell viabilities are,respectively,65.4％and 46.6％on the BMG and Ti6A14V alloy,indicating better biocompatibility of BMG.The Zr60.5Ti3Al9Fe4.5Cu23 BMG with larger GFA,excellent mechanical properties,biocompatibility and bio-corrosion resistance is considered as a potential material in biomedical device fields.