论文部分内容阅读
目的:探讨短时受精与传统过夜受精对体外受精及临床妊娠结局的影响。方法:回顾性分析2012年8月至2014年5月于本中心接受短时受精及传统过夜受精的体外受精(in vitro fertilization,IVF)患者。短时受精IVF组共131周期,传统过夜受精IVF组共129周期,比较两组患者的基本情况、受精、胚胎发育及临床妊娠情况。结果:短时受精IVF组与传统过夜受精IVF组患者正常受精(2 PN)率(68.44%vs 68.23%)、(0 PN)率(21.57%vs 21.99%)、(1 PN)率(6.01%vs 6.08%)、(多PN)率(3.97%vs 3.70%)、受精率(85.24%vs 85.21%),卵裂率(96.65%vs 97.21%)、临床妊娠率(46.85%vs 44.25%)差异均无统计学意义,P均>0.05。短时受精IVF组胚胎利用率(83.45%vs 77.23%)较常规过夜受精IVF组明显升高(P<0.05)。结论:短时受精可能在一定程度上提高卵子利用率,改善胚胎质量从而提高胚胎利用率。
Objective: To investigate the effect of short-term fertilization and traditional overnight fertilization on in vitro fertilization and clinical pregnancy outcome. Methods: A retrospective analysis of in vitro fertilization (IVF) patients undergoing short-term and traditional overnight fertilization at our center from August 2012 to May 2014 was performed. Short-term fertilization of IVF group a total of 131 cycles, the traditional overnight IVF group IVF 129 cycles, the basic situation of two groups were compared, fertilization, embryonic development and clinical pregnancy. RESULTS: The 2 PN rate (68.44% vs 68.23%), (0 PN) rate (21.57% vs 21.99%), (1 PN) rate (6.01%) in IVF group and IVF group were significantly higher than those in IVF group vs 6.08%, rate of multiple PN (3.97% vs 3.70%), fertilization rate (85.24% vs 85.21%), cleavage rate (96.65% vs 97.21%) and clinical pregnancy rate (46.85% vs 44.25% No statistical significance, P> 0.05. The embryo utilization rate of IVF group (83.45% vs 77.23%) was significantly higher than that of IVF group (P <0.05). Conclusion: Short-term fertilization may improve the utilization of ovum to a certain extent, improve embryo quality and improve embryo utilization.