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目的：探讨临床上易误诊为恶性肿瘤的声门上区喉淀粉样变的临床特点及诊治措施。方法对3例声门上区喉淀粉样变患者行喉显微镜下 CO2激光辅助喉部病变切除术，并对临床资料进行分析。结果3例患者均经喉显微镜 CO2激光手术治愈，术后随访1～2年，未复发。结论喉淀粉样变临床表现缺乏特异性，但病理切片刚果红染色阳性可确诊本病；喉显微镜 CO2激光手术是有效的喉淀粉样变治疗手段。“,”Objective To explore the clinical characteristics and treatment of laryngeal amyloidosis (LA)likely to be misdiagnosed as laryngeal malignancy in supragolttic portion.Methods The three patients with LA in supragolttic por-tion received carbon dioxide (CO2 )laser operation with microscopic laryngoscopy to remove the lesions.Relevant clinical data were analyzed.Results All patients recovered clinically.During the follow-up of one to two years,no recurrence occurred.Conclusion LA shows no specific clinical manifestation,whereas it can be confirmed by positive reaction of Congo red staining of pathological section.CO2 laser operation with microscopic laryngoscopy is effective in treating LA.