目的了解当地高中生结核菌素反应性状况。方法选医院驻地县两所中学2146名高一年级学生进行标准化PPD试验调查,并对学生性别、年龄及结核病流行特点进行调查分析。结果74.8%的学生集中在16～17岁组,性别女多于男,来源于农村的学生占63.6%。≥5mm总阳性率28.6%,≥15mm为9.0%。930名无卡痕学生PPD反应在≥5mm、≥10mm、≥15mm和≥20mm分别为20.3%、12.0%、6.6%和2.9%,有卡痕有结核接触史和既往史学生的结素反应均明显高于无卡痕无结核接触史和既往史者。结论把高中新入学学生作为当地结素试验对象,可将≥15mm结素反应者列为预防性治疗对象,以减少结核发病。 Objective To understand the status of tuberculin reactivity in local high school students. Methods A total of 2146 freshmen from two secondary schools in the county hospital were enrolled in the standardized PPD test. The gender, age and prevalence of tuberculosis were also investigated. Results 74.8% of the students were concentrated in the age group of 16-17 years. There were more males and females than females, and 63.6% of them were from rural areas. Total positive rate≥5mm 28.6%, ≥15mm 9.0%. The PPD responses of 930 students without card marks were 20.3%, 12.0%, 6.6% and 2.9% at ≥5mm, ≥10mm, ≥15mm and ≥20mm, respectively. Significantly higher than the no card marks without tuberculosis contact history and past history. Conclusions Taking high school freshmen as the test subjects of local factors can be more than 15mm Jinsuo responders as a preventive treatment to reduce the incidence of tuberculosis.