论文部分内容阅读
神经生长因子(Nerve growth factor,NGF)是最早发现的神经营养因子。它能促进胚胎神经嵴感觉神经元和交感神经节以及基底前脑胆碱能神经元的分化、发育和存活。同时它又是纹状体神经上皮前体和视皮质形成体的增殖因子。NGF对其应答细胞的生物效应都是通过NGF与细胞表面的特异性膜受体相互作用而启动的。依受体糖蛋
Nerve growth factor (NGF) is the earliest discovered neurotrophic factor. It promotes the differentiation, development and survival of embryonic neural crest sensory and sympathetic ganglia and basal forebrain cholinergic neurons. It is also a proliferation factor of striatal neuroepithelial precursors and visual cortex. The biological effects of NGF on its responsive cells are all initiated by the interaction of NGF with specific membrane receptors on the cell surface. According to the receptor glycated egg