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测定了狗的再生肝中肝细胞生长因子（ＣＨＧＦ）不同剂量对肝细胞增殖的刺激作用，发现其与肝细胞增殖的增强有剂量依赖关系；同时，比较了ＣＨＧＦ在－２０℃贮存六个月前后的生物活性，发现－２０℃贮存六个月后，仍保持生物活性；并对ＣＨＧＦ与乳猪肝的肝细胞生长素（ＰＨＧＦ）的生物活性进行了比较，发现二者生物活性基本一致，ＣＨＧＦ的生物活性略高于ＰＨＧＦ的生物活性。
The stimulating effect of different dosages of hepatocyte growth factor (CHGF) on the proliferation of hepatocytes in dogs was measured and found to be dose-dependently related to the enhancement of hepatocyte proliferation. Meanwhile, the effect of CHGF stored at -20 ℃ for six months Biological activity before and after the found that stored at -20 ℃ for six months, still maintain biological activity; CHGF and pig liver liver hepatocyte growth factor (PHGF) biological activity were compared and found that the biological activity of the two basically the same, The biological activity of CHGF is slightly higher than the biological activity of PHGF.