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天然人因子Ⅸ是一种55000—d糖蛋白,它具有—模域结构和许多翻译后修饰。重组型人因子Ⅸ(rFⅨ)是从中国仓鼠卵巢细胞系生产的,该工程细胞具有高水平蛋白加工和表达。为保证重组分子含有血浆衍生型因子Ⅸ的必需结构和功能状态,提出了rFⅨ详细的生物化学和生物物理特性。实验室研
Native human Factor IX is a 55000-d glycoprotein with a domain structure and many post-translational modifications. Recombinant human Factor IX (rFIX) is produced from a Chinese Hamster Ovary cell line that has high levels of protein processing and expression. To ensure that the recombinant molecule contains the necessary structure and functional status of plasma-derived factor IX, the detailed biochemical and biophysical properties of rFIX have been proposed. Laboratory research