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为探讨丁二烯抽提装置中二甲基甲酰胺、丁二烯对作业工人的生殖危害，对丁二烯抽提装置的作业工人１６８人（男１２１人，女４７人）和对照组１９７人（男１３４人，女６３人）进行了生殖危害流行病学调查。结果表明，接触女工妊娠合并恶阻、自然流产、早产发生率高于对照组，有显著性差异（Ｐ＜００５）；接触组男工妻子自然流产、死胎死产发生率高于对照组，有显著性差异（Ｐ＜００５）。提示，二甲基甲酰胺、丁二烯对作业工人具有生殖危害。
In order to investigate the reproductive harm of dimethylformamide and butadiene to working workers in butadiene extraction unit, 168 workers (121 males and 47 females) and the control group 197 People (134 males and 63 females) conducted an epidemiological investigation of reproductive harm. The results showed that there was a significant difference (P <005) in the incidence of pregnancy induced abortion, spontaneous abortion and premature birth among female workers, and the incidence of spontaneous abortion and stillbirth among male workers in contact group was higher than that in control group , There was a significant difference (P <0 05). Prompt, dimethyl formamide, butadiene on the workers have reproductive hazards.