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应用小剂量低浓度Ｐ物质（ｓｕｂｓｔａｎｃｅＰ，ＳＰ）皮内注射法，测定７４例婴幼儿哮喘Ｐ物质皮试强度及其与病情和预后的关系，以提供一种客观而简便的反映婴幼儿哮喘内在神经调节异常的测定方法。结果显示：①Ｐ物质皮试强度与婴幼儿哮喘病。情呈正相关关系；②皮试强度异常增强提示患儿今后有反复喘息发作的可能；③以上二种关系在过敏原皮试阴性患儿中更加明显，说明Ｐ物质皮试配合过敏原皮试在评估婴幼儿哮喘的病情发展和临床处理有一定的指导意义。
The application of low dose and low concentration substance P (SP) intradermal injection method to determine the relationship between the test substance intensity of P substance and the condition and prognosis of 74 cases of infantile asthma to provide an objective and easy to reflect the infant’s asthma intrinsic Determination of neuromodulation disorders. The results showed: ①P substance skin test intensity and infant asthma. Positive correlation between the situation; ② abnormal increase in skin test intensity prompted the possibility of repeated wheezing in children in the future; ③ The above two kinds of relationship in the allergen skin test-negative children even more obvious, indicating substance P skin test with allergens skin test in assessing infant The development of asthma in children and clinical treatment have some guiding significance.