Purpose: To assess the surgical outcomes in patients who underwent lamellar keratoscleroplasty with full-thickness central corneal grafts for limbal dermoids. Design: Retrospective, noncomparative, analysis of a consecutive case series with chart review. Participants: Ten patients (6 male, 4 female; mean age, 12.3±5.0 years; range, 5.7-22.4 years) with 10 limbal dermoids in 10 eyes undergoing lamellar keratoscleroplasty with full-thickness central corneal grafts between 1992 and 2003 at National Taiwan University Hospital were studied. Methods: The medical records and external eye photographs were reviewed. Main Outcome Measur es: Best-corrected visual acuity (BCVA), corneal astigmatism and topography, co smetic outcomes, and surgical complications were measured as outcome indicators. For analysis of the surgical effect on corneal astigmatism, the 9 patients with topographic data available were divided into 2 groups according to their preope rative corneal astigmatism(group 1, < 6 diopters D; group 2, < 6D). Results: The mean earliest recorded BCVA and the latest postoperative BCVA were 6/30 and 6/10, respectively, and the improvement of BCVA after operation combined with amblyopia treatment was 4.9±3.6 lines on a Snellen chart. Patients with preoperative astigmatism > 6.0 D (9.7±1.0 D; n=4) were found to have a marked decrease in astigmatism after surgery (astigmatism change, 5.2±1.7 D). Patients with preoperative astigmatism < 6.0 D (3.4±0.2 D; n=5) were found to have an insignifi-cant increase in astigmatism after surgery (astigmatism change, 0.0±0.6D).After surgery, significant corneal opaci ty was found in 1 patient; mild bluish scleral hue was found in 3 patients. Surgical complications included prolonged reepithelialization, interface neovascular ization, graft rejection, and steroid glaucoma. Conclusions: Using full-thi- ckness central corneal grafts in lamellar keratoscleroplasty for limbal dermoi ds achieved good cosmetic results with limited postoperative complications. Oper ationmay markedly reduce corneal astigmatism in patients with high preoperative corneal astigmatism. Visual prognosis is good in patients undergoing surgery combined with adequate amblyopia treatment. Purpose: To assess the surgical outcomes in patients who underwent lamellar keratoscleroplasty with full-thickness central corneal grafts for limbal dermoids. Design: Retrospective, noncomparative, analysis of a consecutive case series with chart review. Participants: Ten patients (6 male, 4 female ; mean age, 12.3 ± 5.0 years; range, 5.7-22.4 years) with 10 limbal dermoids in 10 eyes undergoing lamellar keratoscleroplasty with full-thickness central corneal grafts between 1992 and 2003 at National Taiwan University Hospital were studied. Methods: The medical records Main Outcome Measur es: Best-corrected visual acuity (BCVA), corneal astigmatism and topography, co smetic outcomes, and surgical complications were measured as outcome indicators. For analysis of the surgical effect on corneal astigmatism, the 9 patients with topographic data available were divided into 2 groups according to their preoperation rane corneal astigmatism (group 1, <6 dio Results: The mean earliest documented BCVA and the latest postoperative BCVA were 6/30 and 6/10, respectively, and the improvement of BCVA after operation combined with amblyopia treatment was 4.9 ± 3.6 lines on Patients with preoperative astigmatism> 6.0 D (9.7 ± 1.0 D; n = 4) were found to have a marked decrease in astigmatism after surgery (astigmatism change, 5.2 ± 1.7 D). Patients with preoperative astigmatism <6.0 D ( 3.4 ± 0.2 D; n = 5) were found to have an insignifi- cant increase in astigmatism after surgery (astigmatism change, 0.0 ± 0.6D). After surgery, significant corneal opaci ty was found in 1 patient; mild bluish scleral hue was found in 3 patients. Surgical complications included prolonged reepithelialization, interface neovascular ization, graft rejection, and steroid glaucoma. Conclusions: Using full-thi- ckness central corneal grafts in lamellar keratoscleroplasty for limbal dermoi ds achieved good cosmetic results with limited postope rativecomplications. Oper ationmay markedly reduced corneal astigmatism in patients with high preoperative corneal astigmatism. Visual prognosis is good in patients undergoing surgery combined with adequate amblyopia treatment.