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作者探索1978年～1987年65岁以上的骨髓增生异常综合征(MDS)及再生漳碍性贫血(AA)的临床资料、鉴别及预后。将MDS分两组:原发性获得性难治性贫血(PARA,55例)+原发性获得性铁粒幼细胞性贫血(PASA,4例)组和原始细胞过多性难治性贫血(RAEB)组(16例),与AA组(12例)相比较,平均年龄分别为76.2±8.6岁、75.1±7.5岁、71.9±9.7岁,三组间无差异。初诊时三组的WBC、Hb、网织红细胞、铁代谢及免疫学检查多项参数无差异。血小板数在AA与MDS两组间有显著差异(P<0.05)。各组的类风湿因子阳性率高,PARA+PASA组抗核抗体阳性率高。PARA+PASA组按生存期分为<1
The authors explored the clinical data, identification and prognosis of patients with myelodysplastic syndrome (MDS) and recurrent aplastic anemia (AA) over the age of 65 from 1978 to 1987. The MDS was divided into two groups: primary acquired refractory anemia (PARA, 55 cases) + primary acquired mitochondrial hematopoietic (PASA, 4 cases) and primed hyperplastic refractory anemia (RAEB) group (16 cases). Compared with AA group (12 cases), the average age was 76.2 ± 8.6 years, 75.1 ± 7.5 years and 71.9 ± 9.7 years, respectively. There was no difference among the three groups. There were no differences in the parameters of WBC, Hb, reticulocyte, iron metabolism and immunological examination in the three groups at the time of first visit. Platelet count was significantly different between AA and MDS groups (P <0.05). The positive rate of rheumatoid factor in each group was high, and the positive rate of antinuclear antibody in PARA + PASA group was high. PARA + PASA group according to the survival period is divided into <1