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对淋巴结无转移，雌激素受体阳性的乳腺癌妇女，连续采用三苯氧胺辅助治疗达五年以上并无益处。这是由美国国立癌症研究所（NCI）根据NationalSurgicalAd-juvantBreastandBowel研究方案B－14的研究资料，于1996年11月公布的结论。NCI认为“连续使用三苯氧胺五年以上，可能产生
For women with breast cancer who have no metastatic lymph nodes and who have estrogen receptor-positive breast cancer, continuous use of tamoxifen for no more than five years has no benefit. This is a conclusion published in November 1996 by the National Cancer Institute (NCI) according to the research data of the National Surgical Ad-juvant BreastandBowel Research Program B-14. NCI believes that "continuous use of tamoxifen for more than five years may result in