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趙承嘏:黃連素如何在黄連中存在中国科学,1951年5月,2卷2期,191—192頁内容摘要——國產黄连中主要有效成份为黄連素(即小蘖鹼),就生物鹼在植物中一般存在狀况而言,多和有機酸如枸橼酸、酒石酸、蘋菓酸、草酸、琥珀酸等相結合而成有機鹽,很少有和无机酸相結合的。本文作者發現,并经用三種試驗方法证明黄連素在黄連中存在情形特殊,是和鹽酸結合而成鹽酸鹽,為生物鹼中所少見,此外本文并载有兩种与前人所得結論相反之實驗,的研究藥物者共同商討。
Zhao Chengyu: How does Berberine exist in Chinese science in Coptidis Rhizoma?, May 1951, Vol. 2, No. 2, pp. 191-192. Abstract: The main active ingredient in domestic Rhizoma Coptidis is berberine (ie, berberine). In general conditions in plants, organic and organic acids such as tannic acid, tartaric acid, malic acid, oxalic acid, and succinic acid are combined to form organic salts, which are rarely combined with inorganic acids. The authors found that the use of three experimental methods to prove that berberine exists in the special case of Coptis chinensis is hydrochloric acid combined into hydrochloride, is rarely found in alkaloids, in addition to containing two different conclusions from previous studies Experiments, study drugs were jointly discussed.