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以D-甘露醇为原料合成(R)-(+)-缩水甘油1。该环氧化合物的亲核开环反应为高立体选择性地(93％～96％e.e.)制备各种手性连二醇提供了一条简便途径。
Synthesis of (R) - (+) - Glycidol 1 from D-Mannitol. The nucleophilic ring-opening reaction of this epoxy compound provides a convenient way to prepare various chiral vicinal diols with high stereoselectivity (93% -96% e.e.).