近年来的研究说明,机体内有一对相互制约、相互拮抗的细胞功能调节因子,即血小板凝集素A_2(T-XA_2和前列腺环素(PGI_2)。TXA_2为血小板聚集最强诱导剂,并有收缩血管作用,由血小板合成,PGI_2则与之相反,为血小板聚集最强抑制剂,有扩张血管作用,由血管内皮细胞合成,血栓的形成过程受 T-XA_2和 PGI_2的调节和控制。凡对抗 TXA_2或增强 P-GI_2的药物必将有利于血栓一栓塞性疾病的防治。 In recent years, studies have shown that there is a pair of mutually-restricted and antagonistic cell function regulators in the body, namely platelet agglutinin A 2 (T-XA 2 and prostacyclin (PGI 2). TXA 2 is the most potent inducer of platelet aggregation and has contraction. Vascular effect, synthesized by platelets, contrary to PGI 2 , is the strongest inhibitor of platelet aggregation, has a vasodilator effect, is synthesized by vascular endothelial cells, and the formation of thrombus is regulated and controlled by T-XA_2 and PGI_2. Or enhance the P-GI 2 drugs will be conducive to the prevention and treatment of thromboembolic diseases.