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基膜聚糖 (lumican)基因在正常上皮细胞和间质细胞均有表达 ,并调节间质细胞分泌基质蛋白。基膜聚糖基因的表达异常可影响细胞基质的形成 ,促使肿瘤发展[1]。本研究对3 2例子宫内膜癌 (内膜癌 )组织及其周围正常内膜组织基膜聚糖基因的表达进行检测 ,以探讨基膜聚糖基因mRNA表
The lumican gene is expressed both in normal epithelial and interstitial cells and regulates the secretion of stromal cells by stromal cells. The abnormal expression of the basement membrane glycoprotein may affect the formation of cell matrix and promote tumor development [1]. In this study, 32 cases of endometrial cancer (endometrial cancer) and its surrounding normal endometrial membrane glycoprotein gene expression was detected in order to explore the basement membrane glycans mRNA