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目的探讨急性脑梗死C反应蛋白水平变化与临床意义。方法 2008年1月至2011收治的符合入选标准的急性脑梗死患者214例,分为轻型急性脑梗死患者104例、中型急性脑梗死患者81例、重型急性脑梗死患者29例。分组于发病72h内进行hs-CRP检测,并于治疗2周后,hs-CRP检测进行比较。结果健康体检组与急性脑梗死组比较P<0.05差异有统计学意义。发病72h内进行hs-CRP检测为(13.284～2.39)mg/L,并于治疗2周后,hs-CRP检测(2.914～1.08)mg/L。经统计学比较P<0.05差异有统计学意义。结论急性脑梗死患者测定血清hc-CRP,浓度的临床意义非常巨大,可以为临床评估急性脑梗死病情的变化及预后提供参考指标。
Objective To investigate the changes and clinical significance of C-reactive protein in acute cerebral infarction. Methods A total of 214 patients with acute cerebral infarction who met the inclusion criteria from January 2008 to January 2011 were divided into mild acute cerebral infarction (104 cases), moderate acute cerebral infarction (81 cases) and severe acute cerebral infarction (29 cases). The hs-CRP test was performed within 72 hours of onset and compared with the hs-CRP test after 2 weeks of treatment. Results There was significant difference between healthy group and acute cerebral infarction group (P <0.05). The detection of hs-CRP was (13.284 ~ 2.39) mg / L within 72 hours of onset, and hs-CRP was detected (2.914 ~ 1.08) mg / L after 2 weeks of treatment. After statistical comparison P <0.05 difference was statistically significant. Conclusion The determination of serum hc-CRP concentration in patients with acute cerebral infarction has great clinical significance. It can provide a reference index for the clinical evaluation of the changes and prognosis of acute cerebral infarction.