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乙型肝炎病毒 (ＨＢＶ)感染是我国常见病及多发病 ,ＨＢＶ难以清除的原因之一就是机体的免疫功能障碍。目前虽然基因重组ＨＢＶ表面抗原 (ＨＢｓＡｇ)疫苗预防ＨＢＶ感染取得了较好的效果 ,但基因重组ＨＢｓＡｇ疫苗主要诱导特异性体液免疫 ,不能刺激机体的细胞免疫应答。近年
Hepatitis B virus (HBV) infection is common and frequently-occurring disease in our country, one of the reasons why HBV is difficult to remove is the immune dysfunction of the body. At present, although the HBsAg vaccine has a good effect in preventing HBV infection, the recombinant HBsAg vaccine mainly induces specific humoral immunity and can not stimulate the cellular immune response. in recent years