论文部分内容阅读
目的 :探索颅内压 (ICP)升高过程中体感诱发电位 (SEPs)与脑干听觉诱发电位 (BAEPs)的变化规律。方法 :采用幕上不同部位放置球囊引起急性ICP增高的动物模型。将新西兰兔 30只分为 3组 :A组动物球囊置入右顶部硬膜下 ;B组动物球囊置入右颞底 ,C组以上部位动物各半 ,球囊内不注水。结果 :(1)A组SEPsP1波幅在ICP升至(1.48± 0 .35 )kPa即发生显著变化 ,而B组中ICP达 (8.10± 1.2 5 )kPa才出现波幅显著压缩。A组BAEPs在ICP升至(9.40± 1.6 0 )kPa时才出现IV ,V ,VII波的PL延长 ,而B组在ICP为 (3.11± 0 .80 )kPa时即见III波PL显著延长。 (2 )随ICP增高 ,P1波幅先随之升高 ,继而转为下降。结论 :SEPs与BAEPs的变化不仅受ICP高低的影响 ,还与病变的部位有关 ;SEPsP1波幅在ICP增高过程中呈先升后降的趋势
Objective: To explore the changes of somatosensory evoked potentials (SEEPs) and brainstem auditory evoked potentials (BAEPs) during intracranial pressure (ICP) elevation. Methods: The animals were placed in different parts of the supratentorial balloon to cause acute ICP increase. 30 New Zealand rabbits were divided into 3 groups: Group A animals placed into the right parietal dura; Group B animals into the right temporal bottom of the balloon, C group of more than half of the parts of the animal, the balloon is not filled with water. Results: (1) The amplitude of SEPsP1 in group A significantly changed when ICP increased to (1.48 ± 0.35) kPa, while that in group B was significantly (8.10 ± 1.25) kPa. BAEPs of group A showed PL prolongation of IV, V and VII waves when ICP increased to (9.40 ± 1.6) kPa, while group B showed a significant prolongation of PL wave III when ICP was (3.11 ± 0.80) kPa. (2) As ICP increased, the amplitude of P1 increased first and then decreased. Conclusion: The changes of SEPs and BAEPs are not only affected by the level of ICP, but also with the location of the lesion. The amplitude of SEPsP1 increases first and then decreases in the process of ICP