论文部分内容阅读
目的:观察黄芪注射液在降低中、晚期恶性肿瘤化疗期毒副反应的效果。方法:将176例经病理诊断明确为恶性肿瘤的患者随机分成2组。治疗组88例,在化疗方案基础上加用黄芪注射液30ml,注入5％GNS中,静脉滴注,每日1次,化疗前一天开始用药。对照组88例,采用单一化疗方法,治疗期不添加任何药物。均以14天为一疗程。结果:外周血白细胞、血小板下降程度明显好于对照组(P<0.05),胃肠反应、脱发、肾功能损伤等与对照组相比明显减轻(P<0.01)。结论:黄芪注射液可明显降低化疗药物的毒副反应,提高机体免疫状态,改善患者的生活、生命质量。
Objective: To observe the effect of astragalus injection in reducing the toxicity of middle and advanced malignant tumor during chemotherapy. Methods: A total of 176 patients with pathologically diagnosed malignant tumors were randomly divided into two groups. The treatment group of 88 cases, on the basis of chemotherapy plus astragalus injection 30ml, injected 5% GNS, intravenous infusion, once daily, the day before chemotherapy medication. The control group of 88 patients, using a single chemotherapy, the treatment period without adding any drug. All 14 days for a course of treatment. Results: The levels of leukocyte and platelet in peripheral blood were significantly lower than those in control group (P <0.05). Gastrointestinal reaction, alopecia and renal dysfunction were significantly decreased compared with control group (P <0.01). Conclusion: Astragalus injection can significantly reduce the toxic and side effects of chemotherapy drugs, improve the immune status and improve patients’ life and quality of life.