本文报道754例婴幼儿健康体检发现心脏杂音251例,杂音发生率为33.27％,其中3例为器质性杂音,5例可疑器质性杂音。通过10年追踪,诊断为室间隔缺损者5例,房间隔缺损1例,法鲁氏四联症1例,二尖瓣脱垂1例。有236例心脏杂音均在15岁前消失,其杂音消失率为94.02％。追踪中还发现杂音消失时间与青春发育期有肯定关系。文中还就其杂音的定义、临床特征、发病机理及对无害性杂音的认识问题做了扼要的讨论。 This article reports 754 cases of infants physical examination found 251 cases of heart murmur, the incidence of noise was 33.27%, of which 3 cases of organic murmur, 5 cases of suspicious organic murmur. After 10 years of follow-up, 5 cases were diagnosed as ventricular septal defect, 1 case was atrial septal defect, 1 case was tetralogy of Fallot and 1 case was mitral valve prolapse. There are 236 cases of heart murmur disappeared before the age of 15, the noise disappearance rate was 94.02%. Tracing also found that the disappearance of noise and puberty have a positive relationship. The article also briefly discusses the definition of murmur, clinical features, pathogenesis and understanding of innocuous murmur.