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BACKGROUND:Multimodal treatment of patients with glioblastoma multiforme(GBM)allows an increasingnumber of patients to survive beyond one year.On account of vari0us neurological and psychophysiological im-pairments,however,these patients may not benefit in terms of quality of life(QOL).We evaluated the subjectiveQOL,clinical psychophysiological and cognitive functions in patients with GBM surviving 18 months after diagno-sis.PATIENTS AND METHODS:Thirteen patients underwent psychophysiological and psychometric measurementsfor central-nervous activation,habituation of skin-conductance reaction,crystallized intelligence,verbal and
BACKGROUND: Multimodal treatment of patients with glioblastoma multiforme (GBM) allows an increasing number of patients to survive beyond one year. Of account of vari0us neurological and psychophysiological im-pairments, however, these patients may not benefit in terms of quality of life (QOL) . We evaluated the subjectiveQOL, clinical psychophysiological and cognitive functions in patients with GBM surviving for 18 months after diagno-sis. PATIENTS AND METHODS: Thirteen patients underwent psychophysiological and psychometric measurements for central-nervous activation, habituation of skin-conductance reaction, crystallized intelligence, verbal and