目的探讨原发性甲状旁腺功能亢进症的临床治疗方式,分析其科学性与有效性,为临床提供指导。方法选取我院2012年1月~2013年6月收治的原发性甲状旁腺功能亢进症者25例,收集其临床资料包括治疗手段、效果等并进行分析。结果手术情况:25例患者全部接受手术治疗,其中颈部探查术11例,囊肿切除术2例,癌根治术2例,腺瘤直接切除术10例;效果:所有患者均痊愈,效果显著,无1例出现死亡。经3个月~23年的随访未发现复发病例。结论原发性甲状旁腺功能亢进症较为少见,通过早期明确诊断,采取措施及时救治,维持有效的血液循环量,结合外科手术治疗可提高治愈率,降低致残率和死亡率。 Objective To investigate the clinical treatment of primary hyperparathyroidism, analyze its scientific and effectiveness, and provide guidance for clinical practice. Methods Twenty-five patients with primary hyperparathyroidism admitted in our hospital from January 2012 to June 2013 were selected and their clinical data, including treatment methods and effects, were collected and analyzed. Results All the 25 cases underwent surgical treatment. Among them, 11 cases were neck exploration, 2 cases were cyst excision, 2 cases were radical resection and 10 cases were direct adenoidectomy. Results: All patients recovered well, No one died. After 3 months to 23 years of follow-up found no recurrence. Conclusions Primary hyperparathyroidism is rare. Through early diagnosis, timely treatment and maintenance of effective blood circulation, combined with surgical treatment can improve the cure rate and reduce the morbidity and mortality.